Luveris

Description: Luveris (lutropin alfa for injection) is a recombinant human luteinizing hormone (rhLH). Each package of Luveris is comprised of a vial of powdered medication containing 82.5 IU (International Units) and a 1cc vial of Sterile Water for injection, USP (diluent). After mixing the powdered Luveris with the 1cc of diluent, the product will deliver 75 IU of rhLH. It is formulated for subcutaneous injection.

How It Works: Luveris is indicated for use in combination with gonadotropins to help stimulate follicular development in the ovaries of hypogonadotropic hypogonadal women with profound LH and FSH deficiency. It works by stimulating the theca cells (outer cell wall of the follicle) to secrete androgens, which will be used by the granulosa cells (part of the theca cells) to produce estradiol which will support the FSH induced follicular development.

Potential Side Effects: Side effects that may occur include: nausea, vomiting, diarrhea, fever, breast tenderness, spotting or menstrual changes, ovarian enlargement, and injection site reaction (pain, swelling or irritation). Treatment with Luveris may increase the likelihood of multiple births. The risk of ovarian hyperstimulation syndrome (OHSS) should be discussed with your physician prior to treatment. Early warning signs include severe pelvic pain, nausea, vomiting and weight gain.

 

If you experience an allergic reaction: difficulty breathing; closing of throat; swelling of lips, tongue or face; or hives; seek emergency attention immediately. And if at any time you experience pain, warmth, redness, numbness, or tingling in an arm or leg; confusion, severe dizziness or severe headache, seek medical attention immediately.

PLEASE NOTE: If these or any other side effects occur, contact your physician.

Storage: Store Luveris at room temperature or refrigerate. Protect from light. Luveris cannot be mixed in advance. Once it is mixed, it must be used immediately.

Written Injection Instructions